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Status migrainosus

MedGen UID:
137900
•Concept ID:
C0338489
•
Disease or Syndrome
Synonym: Status Migrainosus
SNOMED CT: Status migrainosus (230467008); Status migrainus (230467008)

Definition

An episode of migraine that persists for more than 72 hours. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStatus migrainosus

Professional guidelines

PubMed

Emergency Department and Inpatient Management of Headache in Adults.
Robblee J, Grimsrud KW
Curr Neurol Neurosci Rep 2020 Mar 18;20(4):7. doi: 10.1007/s11910-020-01030-w. PMID: 32189074
Emergency Department and Inpatient Management of Status Migrainosus and Intractable Headache.
Rozen TD
Continuum (Minneap Minn) 2015 Aug;21(4 Headache):1004-17. doi: 10.1212/CON.0000000000000191. PMID: 26252587
Treatment of status migrainosus.
Marcus DA
Expert Opin Pharmacother 2001 Apr;2(4):549-55. doi: 10.1517/14656566.2.4.549. PMID: 11336606

Recent clinical studies

Etiology

Status migrainosus.
Kamourieh S, Rozen T, Anderson JM
Handb Clin Neurol 2024;199:413-439. doi: 10.1016/B978-0-12-823357-3.00017-3. PMID: 38307660
Approach to Pediatric Intractable Migraine.
Alqahtani M, Barmherzig R, Lagman-Bartolome AM
Curr Neurol Neurosci Rep 2021 Jun 4;21(8):38. doi: 10.1007/s11910-021-01128-9. PMID: 34089140
Status Migrainosus in Children and Adults.
Chua AL, Grosberg BM, Evans RW
Headache 2019 Oct;59(9):1611-1623. doi: 10.1111/head.13676. PMID: 31603553
Pediatric Inpatient Headache Therapy: What is Available.
Kabbouche M
Headache 2015 Nov-Dec;55(10):1426-9. Epub 2015 Oct 31 doi: 10.1111/head.12701. PMID: 26517974
Emergency Department and Inpatient Management of Status Migrainosus and Intractable Headache.
Rozen TD
Continuum (Minneap Minn) 2015 Aug;21(4 Headache):1004-17. doi: 10.1212/CON.0000000000000191. PMID: 26252587

Diagnosis

Status migrainosus.
Kamourieh S, Rozen T, Anderson JM
Handb Clin Neurol 2024;199:413-439. doi: 10.1016/B978-0-12-823357-3.00017-3. PMID: 38307660
Managing and Preventing Migraine in the Emergency Department: A Review.
Cortel-LeBlanc MA, Orr SL, Dunn M, James D, Cortel-LeBlanc A
Ann Emerg Med 2023 Dec;82(6):732-751. Epub 2023 Jul 11 doi: 10.1016/j.annemergmed.2023.05.024. PMID: 37436346
Approach to Pediatric Intractable Migraine.
Alqahtani M, Barmherzig R, Lagman-Bartolome AM
Curr Neurol Neurosci Rep 2021 Jun 4;21(8):38. doi: 10.1007/s11910-021-01128-9. PMID: 34089140
Headaches in pregnancy.
Silberstein SD
Neurol Clin 2004 Nov;22(4):727-56. doi: 10.1016/j.ncl.2004.06.001. PMID: 15474764
Migraine and pregnancy.
Silberstein SD
Neurol Clin 1997 Feb;15(1):209-31. doi: 10.1016/s0733-8619(05)70305-4. PMID: 9058407

Therapy

Status migrainosus.
Kamourieh S, Rozen T, Anderson JM
Handb Clin Neurol 2024;199:413-439. doi: 10.1016/B978-0-12-823357-3.00017-3. PMID: 38307660
Treating status migrainosus in the emergency setting: what is the best strategy?
Vécsei L, Szok D, Nyári A, Tajti J
Expert Opin Pharmacother 2018 Oct;19(14):1523-1531. Epub 2018 Sep 10 doi: 10.1080/14656566.2018.1516205. PMID: 30198804
Pediatric Inpatient Headache Therapy: What is Available.
Kabbouche M
Headache 2015 Nov-Dec;55(10):1426-9. Epub 2015 Oct 31 doi: 10.1111/head.12701. PMID: 26517974
Emergency Department and Inpatient Management of Status Migrainosus and Intractable Headache.
Rozen TD
Continuum (Minneap Minn) 2015 Aug;21(4 Headache):1004-17. doi: 10.1212/CON.0000000000000191. PMID: 26252587
Treatment of status migrainosus.
Marcus DA
Expert Opin Pharmacother 2001 Apr;2(4):549-55. doi: 10.1517/14656566.2.4.549. PMID: 11336606

Prognosis

Incidence of Status Migrainosus in Olmsted County, Minnesota, United States: Characterization and Predictors of Recurrence.
VanderPluym JH, Mangipudi K, Mbonde AA, Gritsch D, Caronna E, Halker Singh RB, Butterfield RJ, Smith JH
Neurology 2023 Jan 17;100(3):e255-e263. Epub 2022 Sep 29 doi: 10.1212/WNL.0000000000201382. PMID: 36175145Free PMC Article
The Profile and Prognosis of Youth With Status Migrainosus: Results From an Observational Study.
Orr SL, Turner A, Kabbouche MA, Horn PS, O'Brien HL, Kacperski J, LeCates S, White S, Weberding J, Miller MN, Powers SW, Hershey AD
Headache 2020 May;60(5):878-888. Epub 2020 Feb 7 doi: 10.1111/head.13767. PMID: 32031255
New Daily Persistent Headache: a Diagnostic and Therapeutic Odyssey.
Riddle EJ, Smith JH
Curr Neurol Neurosci Rep 2019 Mar 19;19(5):21. doi: 10.1007/s11910-019-0936-9. PMID: 30888529
Impact of Aura and Status Migrainosus on Readmissions for Vascular Events After Migraine Admission.
Velickovic Ostojic L, Liang JW, Sheikh HU, Dhamoon MS
Headache 2018 Jul;58(7):964-972. Epub 2018 Jun 22 doi: 10.1111/head.13347. PMID: 29933509
Status migrainosus and migraine aura status in a French tertiary-care center: An 11-year retrospective analysis.
Beltramone M, Donnet A
Cephalalgia 2014 Jul;34(8):633-7. Epub 2014 Feb 6 doi: 10.1177/0333102414520763. PMID: 24504530

Clinical prediction guides

Peripheral Nerve Blocks: A Tool for Inpatient Pediatric Status Migrainosus.
Goenka A, Chikkannaiah M, Fonseca LD, Kumar G
Pediatr Neurol 2023 Jan;138:81-86. Epub 2022 Oct 28 doi: 10.1016/j.pediatrneurol.2022.10.010. PMID: 36423569
Unrecognized challenges of treating status migrainosus: An observational study.
Iljazi A, Chua A, Rich-Fiondella R, Veronesi M, Melo-Carrillo A, Ashina S, Burstein R, Grosberg B
Cephalalgia 2020 Jul;40(8):818-827. Epub 2020 Mar 12 doi: 10.1177/0333102420911461. PMID: 32162976Free PMC Article
The Profile and Prognosis of Youth With Status Migrainosus: Results From an Observational Study.
Orr SL, Turner A, Kabbouche MA, Horn PS, O'Brien HL, Kacperski J, LeCates S, White S, Weberding J, Miller MN, Powers SW, Hershey AD
Headache 2020 May;60(5):878-888. Epub 2020 Feb 7 doi: 10.1111/head.13767. PMID: 32031255
New Daily Persistent Headache: a Diagnostic and Therapeutic Odyssey.
Riddle EJ, Smith JH
Curr Neurol Neurosci Rep 2019 Mar 19;19(5):21. doi: 10.1007/s11910-019-0936-9. PMID: 30888529
Impact of Aura and Status Migrainosus on Readmissions for Vascular Events After Migraine Admission.
Velickovic Ostojic L, Liang JW, Sheikh HU, Dhamoon MS
Headache 2018 Jul;58(7):964-972. Epub 2018 Jun 22 doi: 10.1111/head.13347. PMID: 29933509

Recent systematic reviews

The place of corticosteroids in migraine attack management: A 65-year systematic review with pooled analysis and critical appraisal.
Woldeamanuel YW, Rapoport AM, Cowan RP
Cephalalgia 2015 Oct;35(11):996-1024. Epub 2015 Jan 9 doi: 10.1177/0333102414566200. PMID: 25576463
Where is dihydroergotamine mesylate in the changing landscape of migraine therapy?
Morren JA, Galvez-Jimenez N
Expert Opin Pharmacother 2010 Dec;11(18):3085-93. doi: 10.1517/14656566.2010.533839. PMID: 21080856
Treatment of children with migraine in the emergency department: a qualitative systematic review.
Bailey B, McManus BC
Pediatr Emerg Care 2008 May;24(5):321-30. doi: 10.1097/PEC.0b013e31816ed047. PMID: 18496120

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